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Research paper · Foundational
RNA-guided human genome engineering via Cas9
The companion January 2013 paper from George Church's laboratory, published the same day.
Simple explanation
Published in the same issue of the same journal as the Zhang laboratory's paper, this independently showed CRISPR editing human cells. Two groups arriving at the same result at the same time is a good sign that a result is real.
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Mali, Yang, Esvelt, Aach, Guell, DiCarlo, Norville and Church demonstrated Cas9-mediated editing in human cells, including in induced pluripotent stem cells, and characterised guide RNA requirements.
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This page is a reference, not medical advice. Research and regulatory status change; check the last-updated date above and confirm anything important against the primary sources listed.